Figure 4.

High correspondence between plus2 array and quantitative proteomics data mapped by peptide proximity. Each point corresponds to a matched probeset-peptide pair. A mapping was made when the genomic-origin of a peptide was within 1000 base pairs of the genome location of a microarray probeset. X and Y axes: fold-changes between MCF7 and MCF10A for the microarray data and the quantitative proteomics data, respectively. When more than one matching probeset was found for a given peptide, the mean value was calculated. r: Pearson correlation. n: number of data points. No error bars are shown because no averaging was performed because mapping was based on probeset/peptide location, rather than higher level features such as transcripts or exons, which provide a rationale strategy for grouping the peptides/probesets.