Figure 4.

CRE prediction by ReAlignerV followed by experimental validation. The 8-kb genomic sequences upstream of the translation start sites of human and mouse CCL3 genes were aligned, and the alignments were integrated with results from RepeatMasker and TRANSFAC Match searches by ReAlignerV. In this prediction, only CRE sites were searched for by TRANSFAC Match (A), and two conserved CRE sites, shown in red squares (B), were found to be functional by an experimental study.