A structural analysis of in vitro catalytic activities of hammerhead ribozymes

doi:10.1186/1471-2105-8-469

BMC Bioinformatics

Volume 8

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Research article

A structural analysis of in vitro catalytic activities of hammerhead ribozymes

Yu Shao^* , Susan Wu^* , Chi Yu Chan , Jessie R Klapper , Erasmus Schneider and Ye Ding

Wadsworth Center, New York State Department of Health, 150 New Scotland Avenue, Albany, NY 12208, USA

author email corresponding author email* Contributed equally

BMC Bioinformatics 2007, 8:469doi:10.1186/1471-2105-8-469


Published:	30 November 2007

Additional files

Additional File 1:

A representative gel. In-vitro transcribed and purified ribozymes were analyzed by denaturing gel electrophoresis. The figure shows a representative gel with four different ribozymes.

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Additional File 2:

Sequences of hammerhead ribozymes. The table lists sequences of 15 hammerhead ribozymes targeted to the BCRP mRNA.

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Additional File 3:

Primer sequences for RT-PCR amplification. The table lists primer sequences for RT-PCR amplification of the ribozymes for quantifying cleavage reaction.

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