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Open AccessHighly AccessMethodology article

Transcription factor target prediction using multiple short expression time series from Arabidopsis thaliana

Henning Redestig1 email, Daniel Weicht1 email, Joachim Selbig1,2 email and Matthew A Hannah1 email

1Max Planck Institute for Molecular Plant Physiology, Am Mühlenberg 1, D-14476 Potsdam-Golm, Germany

2University of Potsdam, Am Neuen Palais, D-14469, Potsdam, Germany

author email corresponding author email

BMC Bioinformatics 2007, 8:454doi:10.1186/1471-2105-8-454

Published: 18 November 2007

Additional files

Additional file 1:

Literature study of transcription factors and their targets considered in this study. We focused on TFs that have previously been implicated in stress responses, but as not all respond under the conditions used to generate the AtGenExpress dataset, some were therefore excluded from our test set. Wherever multiple genes were knocked out or over-expressed, or where functional redundancy has been implicated, the average of those genes was used.

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Additional file 2:

The numbers of over-represented hexamers and annotations (MapMan bins) in the experimentally defined regulons. With randomly chosen genes we would not expect any over-representation. A clear majority of the larger regulons have several over-represented hexamers annotations. 'OX' indicates that the targets were found using over-expression, 'KO' using knock-out and 'ChIP' using ChIP-chip experiment.

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