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Open AccessHighly AccessResearch article

Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors

Xueping Yu1 email, Jimmy Lin1 email, Donald J Zack1,2,3,4 email and Jiang Qian1 email

Wilmer Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA

Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA

Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA

McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA

author email corresponding author email

BMC Bioinformatics 2007, 8:437doi:10.1186/1471-2105-8-437

Published: 9 November 2007

Additional files

Additional file 1:

Tissue specific genes. These preferentially expressed genes in 30 human tissues were derived from EST database using methods described in previous work [22].

Format: XLS Size: 238KB Download file

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Additional file 2:

Tissue specific TF interactions. These significant TF pairs were calculated according to their overrepresented co-occurrence and distance constraint [22].

Format: XLS Size: 1.2MB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 3:

Predictions of tissue specific CRMs.

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Additional file 4:

Enriched functional categories in cCRMs and ncCRMs whose target genes' conservation scores are greater than 0.5.

Format: XLS Size: 16KB Download file

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