Research article
Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors
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* Corresponding author: Jiang Qian jiang.qian@jhmi.edu
1 Wilmer Institute, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
2 Department of Molecular Biology and Genetics, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
3 Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
4 McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
BMC Bioinformatics 2007, 8:437 doi:10.1186/1471-2105-8-437
Published: 9 November 2007Additional files
Additional file 1:
Tissue specific genes. These preferentially expressed genes in 30 human tissues were derived from EST database using methods described in previous work [22].
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Additional file 2:
Tissue specific TF interactions. These significant TF pairs were calculated according to their overrepresented co-occurrence and distance constraint [22].
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Additional file 3:
Predictions of tissue specific CRMs.
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Additional file 4:
Enriched functional categories in cCRMs and ncCRMs whose target genes' conservation scores are greater than 0.5.
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