Table 3

Kinetic data for 10 different Class I Fructose-1,6-bisphosphate aldolases (FBA) with fructose-1,6-bisphosphate as substrate

Organism

K_m (mM)

k_cat (s^-1)

k_cat/K_m (10⁶ M^-1s^-1)

SwissProt ID Sequence identity to 1zaiA

Reference

Trypanosoma brucei

0.0092

10.3

1.12

ALF_TRYBB 49%

[65]

Oryctolagus cuniculus

0.0095

10.2

1.07

ALDOA_RABIT 100%

[35]

Oryctolagus cuniculus

0.00084

2.94

3.50

ALDOB_RABIT 71%

[35]

Entosphenus japonicus

0.018

46.1

2.56

ALF1_LAMJA 75%

[66]

Entosphenus japonicus

0.0048

15.8

3.29

ALF2_LAMJA 74%

[66]

Leishmania mexicana

0.049

8.2

0.167

Q9U5N6_LEIME 49%

[67]

Rattus norvegicus

0.0089

33

3.71

ALDOC_RAT 81%

[68]

Homo sapiens

0.052

59.7

1.15

ALDOA_HUMAN 98%

[68]

Homo sapiens

0.012

20.1

1.68

ALDOB_HUMAN 69%

[68]

Homo sapiens

0.013

12.6

0.969

ALDOC_HUMAN 82%

[68]

Gabdoulline et al. BMC Bioinformatics 2007 8:373   doi:10.1186/1471-2105-8-373