Table 4

Amino acid groupings (11 groups) according to their physical and chemical properties


Amino acids

Hydrophobic (hb)

F, I, W, L, V, M, Y, C, A

Hydrophilic (hp)

R, K, N, D, E, P

Charged (Ch)

R, H, K, D, E

Neutral (Neu)

T, H, G, S, Q

Aliphatic (Ali)

I, L, V

Aromatic (Aro)

F, W, Y, H

Polar (Pol)

N, Q, R, E, D

Nonpolar (Npol)

F, M, I, L, V

Polar-Nonpolar (PN)

C, K, H, Y, W

Small (Sm)

P, V, A, G, T, S, N, D

Cysteine (cys)


Pugalenthi et al. BMC Bioinformatics 2007 8:351   doi:10.1186/1471-2105-8-351

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