SPICE displays a multiple structure alignment of the Saposins, as provided by the SISYPHUS database. It is possible to choose which of the structures should be superimposed and sequence features can be mapped on the three dimensional alignment. The top of the image shows the different DAS commands that are being used in order to obtain the integration of the data.
Prlić et al. BMC Bioinformatics 2007 8:333 doi:10.1186/1471-2105-8-333