BMC Bioinformatics

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Portraits of breast cancer progression

Gul S Dalgin, Gabriela Alexe, Daniel Scanfeld, Pablo Tamayo, Jill P Mesirov, Shridar Ganesan, Charles DeLisi and Gyan Bhanot*

BMC Bioinformatics 2007, 8:291 doi:10.1186/1471-2105-8-291

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Evidence that molecular changes in cells occur before morphological alterations during the progression of breast ductal carcinoma

Nadia P Castro, Cynthia ABT Osório, César Torres, Elen P Bastos, Mário Mourão-Neto, Fernando A Soares, Helena P Brentani, Dirce M Carraro Breast Cancer Research 2008, 10:R87 (17 October 2008)

Potentially invasive cells from ductal carcinoma in situ exhibit modifications in the general gene expression pattern before visible morphological alteration of the lesion, predicting the carcinoma progression risk.