Table 2

Performance of the five methods in simulation


Method of Analysis

Percentage arrays damaged
Single Channel
Unaffected Data
Inclusive
Combined (kest)
Combined (kfix = 0.5)
Combined (kfix = 0.25)

20
85,780
88,197
86,899
88,393
87,763
88,017
40
85,776
86,592
84,557
88,296
87,317
87,704
60
85,799
83,958
82,650
88,054
86,765
87,402
80
85,893
78,134
80,411
87,252
86,016
86,848







All Simulations
343,248
336,881
334,517
351,995
347,861
349,971

Presented are the numbers of differentially expressed genes that would be identified by taking a list of the top 4,000 genes in each case. Recall that there are indeed 4,000 differentially expressed genes, so the numbers are out of 100,000 (25 times 4,000) for the sub experiments and out of 400,000 (100 times 4,000) overall.

Lynch et al. BMC Bioinformatics 2007 8:26   doi:10.1186/1471-2105-8-26