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Open AccessResearch article

Reuse of structural domain–domain interactions in protein networks

Benjamin Schuster-Böckler email and Alex Bateman email

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK

author email corresponding author email

BMC Bioinformatics 2007, 8:259doi:10.1186/1471-2105-8-259

Published: 18 July 2007

Additional files

Additional file 1:

iPfam_pair_frequencies. En Excel file containing the frequencies of all iPfam domain pairs for all five species, i.e. the number of interactions that contain the respective iPfam domain pair.

Format: XLS Size: 211KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 2:

iPfam_architectures. Two Excel sheets containing the frequencies of all iPfam domain architectures in S. cerevisiae and H. sapiens experimental interactions, i.e. the number of proteins that are composed of a certain set of iPfam domains.

Format: XLS Size: 109KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 3:

iPfam_pair_conservation. An Excel spreadsheet containing the 107 iPfam domain pairs conserved amongst E. coli, S. cerevisiae and H. sapiens and their frequencies.

Format: XLS Size: 16KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 4:

iPfam_frequencies. An Excel file containing the frequencies of each of the iPfam domains for all five species, i.e. the number of proteins containing the respective domain.

Format: XLS Size: 270KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 5:

iPfam_inter-intrachain. An Excel file listing the number of interchain and intrachain interactions in all PDB structures for each iPfam domain pair.

Format: XLS Size: 395KB Download file

This file can be viewed with: Microsoft Excel Viewer


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