Table 1

Summary results for performance comparisons between SCOPE and its component algorithms, on all regulons. A "Win" is a regulon for which a program had the highest accuracy and that accuracy was at least 0.10. Programs in a two-way tie are credited with 0.5 wins each, so by construction, SCOPE can at best share a win with one of the other programs. A perfect winner-take-all ensemble method would have the same number of wins as all the component algorithms combined. A "clear win (loss)" is a regulon for which SCOPE's accuracy was at least 0.10 higher (lower) than the other program. The p-value reported for the paired t-test was Bonferroni-corrected to account for multiple (three) comparisons.

SCOPE

BEAM

PRISM

SPACER


Average

0.24

0.17

0.18

0.17

Stderr

0.02

0.02

0.02

0.02

Wins

20

13

11

17

scores ≥ 0.50

8

8

6

5

scores ≥ 0.33

21

15

14

14

scores ≥ 0.20

39

23

23

26

Regulons returned

78

78

78

78

clear win for SCOPE vs

-

28

18

19

clear loss for SCOPE vs

-

6

2

3

t-test p-value

-

0.002

0.002

0.004


Chakravarty et al. BMC Bioinformatics 2007 8:249   doi:10.1186/1471-2105-8-249

Open Data