Table 5

Data included in the benchmark calculation.

HLA-DR alleles

IEDB

# Binders

SYFPEITHI


DRB1*0101

1203

920

33

DRB1*0301

474

65

22

DRB1*0401

457

209

65

DRB1*0404

168

74

23

DRB1*0405

171

88

23

DRB1*0701

310

125

34

DRB1*0802

174

58

1

DRB1*0901

117

47

13

DRB1*1101

359

95

23

DRB1*1302

179

101

20

DRB1*1501

365

188

12

DRB3*0101

102

3

2

DRB4*0101

181

74

5

DRB5*0101

343

112

11

H2-IAb

76

43

47

H2-IAd

342

56

7

H2-IAs

126

35

19


The first column gives the allele name, the second to fourth columns the number of unique peptide data, and binders included for each allele in the IEDB [13] and SYFPEITHI [33] databases, respectively. Binding peptides were identified using an IC50 binding threshold of 500 nM.

Nielsen et al. BMC Bioinformatics 2007 8:238   doi:10.1186/1471-2105-8-238

Open Data