Methodology article
A Three Stage Integrative Pathway Search (TIPS©) framework to identify toxicity relevant genes and pathways
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* Corresponding author: Christina Chan krischan@egr.msu.edu
1 Department of Chemical Engineering and Materials Science, Michigan State University, East Lansing, MI 48824, USA
2 Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA
3 Department of Computer Science and Engineering, Michigan State University, East Lansing, MI 48824, USA
4 MetagenX LLC. Okemos, MI, 48864, USA
5 Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI 48824, USA
6 National Institute on Alcohol Abuse and Alcoholism (NIAAA/NIH), 5625 Fishers Lane, Rockville, MD 20851, USA
BMC Bioinformatics 2007, 8:202 doi:10.1186/1471-2105-8-202
Published: 14 June 2007Additional files
Additional file 1:
ICA gene weights. Additional file 1 is a list of the gene weights determined by ICA.
Format: XLS Size: 150KB Download file
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Additional file 2:
Important gene list. Additional file 2 is a list of important genes determined manually with a literature review.
Format: XLS Size: 155KB Download file
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Additional file 3:
Genes selected by ANOVA. Additional file 3 lists 830 genes selected by ANOVA analysis.
Format: XLS Size: 123KB Download file
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Additional file 4:
Normality test. Additional file 4 presents the normality test of the gene data.
Format: DOC Size: 111KB Download file
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Additional file 5:
Network learned by LibB. Additional file 5 presents the network learned by search and score method of LibB.
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