Table 2

Distribution of different tissue/function-specific TF groups among AMP families

Tissue/function-specific TF groups

Cut-Off [%]

AD

NHR

CC

IMM

LIV

LUNG

MUS

NS

PAN

PIT

EYE

BS

Total no. of motifs

131

139

97

122

141

122

78

143

77

74

1

12

No. of AMPcg families

17

18

8

14

19

16

4

17

5

5

0

0

25

14

12

7

11

14

10

4

15

3

2

0

0

30

8

11

3

6

10

5

2

11

2

1

0

0

35

4

7

3

4

3

4

1

9

0

0

0

0

40

Tissue/function-specific TF groups are AD: adipocyte-related TFs; NHR: nuclear hormone receptor TFs; CC: cell cycle-related TFs; IMM: immune cell-specific TFs; LIV: liver cell-specific TFs; LUNG: lung cell-specific TFs; MUS: muscle cell-specific TFs; NS: nervous system-related TFs; PAN: pancreatic B-cell related; PIT: pituitary gland-specific TFs; Eye: eye-specific TFs; BS: bone-specific TFs. TF that groups (AD, NHR etc.) occur with highest frequency among AMP families are underlined. Cut-off indicates the minimum percentage of motifs in a TF family that can bind TFs from a particular tissue/function-specific group.

Brahmachary et al. BMC Bioinformatics 2006 7(Suppl 5):S8   doi:10.1186/1471-2105-7-S5-S8