Additional File 2.

Prediction errors as a function of DPI tolerance. The number of inferred errors, NFP + NFN, are plotted as a function of the DPI tolerance, τ, for (a) the Erdös-Rényi and (b) the scale-free topologies. Raising τ to a value of 0.2 results in a modest increase in false positives, while larger values of τ produce a much sharper increase. Therefore, a moderate choice for the tolerance can help elucidate additional interactions without introducing an excessive number of false positives. Results are calculated for a statistical significance threshold of 10-4 and a synthetic microarray size of 1,000.

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Margolin et al. BMC Bioinformatics 2006 7(Suppl 1):S7   doi:10.1186/1471-2105-7-S1-S7