BMC Bioinformatics

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Statistical analysis of real-time PCR data

Joshua S Yuan, Ann Reed, Feng Chen and C Neal Stewart*

BMC Bioinformatics 2006, 7:85 doi:10.1186/1471-2105-7-85

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BioMed Central: 18 citations

Primary research   Open Access

5-alpha-reductase type I (SRD5A1) is up-regulated in non-small cell lung cancer but does not impact proliferation, cell cycle distribution or apoptosis

Friedrich G Kapp, Anette Sommer, Thomas Kiefer, Gottfried Dölken, Bernard Haendler Cancer Cell International 2012, 12:1 (18 January 2012)

Research article   Open Access

Adaptation of barley to mild winters: A role for PPDH2

M Cristina Casao, Ildiko Karsai, Ernesto Igartua, M Pilar Gracia, Otto Veisz, Ana M Casas BMC Plant Biology 2011, 11:164 (18 November 2011)

Research   Open Access

Nogo receptor is involved in the adhesion of dendritic cells to myelin

Claire L McDonald, Karin Steinbach, Florian Kern, Rüdiger Schweigreiter, Roland Martin, Christine E Bandtlow, Markus Reindl Journal of Neuroinflammation 2011, 8:113 (9 September 2011)

Research   Open Access

Canine distemper virus induces apoptosis in cervical tumor derived cell lines

Helen L Del Puerto, Almir S Martins, Amy Milsted, Elaine M Souza-Fagundes, Gissandra F Braz, Barbara Hissa, Luciana O Andrade, Fabiana Alves, Daniela S Rajão, Rômulo C Leite, Anilton C Vasconcelos Virology Journal 2011, 8:334 (30 June 2011)

Methodology article   Open Access

Efficiency clustering for low-density microarrays and its application to QPCR

Eric F Lock, Ryan Ziemiecki, JS Marron, Dirk P Dittmer BMC Bioinformatics 2010, 11:386 (20 July 2010)

Research article   Open Access

Muscle transcriptomic profiles in pigs with divergent phenotypes for fatness traits

Angela Cánovas, Raquel Quintanilla, Marcel Amills, Ramona N Pena BMC Genomics 2010, 11:372 (11 June 2010)

Research article   Open Access

Transcription profiling provides insights into gene pathways involved in horn and scurs development in cattle

Maxy Mariasegaram, Antonio Reverter, Wes Barris, Sigrid A Lehnert, Brian Dalrymple, Kishore Prayaga BMC Genomics 2010, 11:370 (11 June 2010)

Research article   Open Access

Identification and characterization of Dlc1 isoforms in the mouse and study of the biological function of a single gene trapped isoform

Mohammad G Sabbir, Nichola Wigle, Shauna Loewen, Yuan Gu, Cordula Buse, Geoffrey G Hicks, Michael RA Mowat BMC Biology 2010, 8:17 (3 March 2010)

Embryonic development fails in mice deficient in a single isoform of the tumour suppressor Dlc1, with defects in brain, heart and placental blood vessels indicating an essential in vivo role for this Rho GTPase activating protein.

Research article   Open Access Highly Accessed

'Who's who' in two different flower types of Calluna vulgaris (Ericaceae): morphological and molecular analyses of flower organ identity

Thomas Borchert, Katrin Eckardt, Jörg Fuchs, Katja Krüger, Annette Hohe BMC Plant Biology 2009, 9:148 (14 December 2009)

The economically important bud-flowering variety of Calluna vulgaris has two whorls of colored sepals instead of petals, and an absence of stamens which cannot be explained by modified spatial expression of known organ identity genes.

Proceedings   Open Access Highly Accessed

Comparative genome analysis of lignin biosynthesis gene families across the plant kingdom

Zhanyou Xu, Dandan Zhang, Jun Hu, Xin Zhou, Xia Ye, Kristen L Reichel, Nathan R Stewart, Ryan D Syrenne, Xiaohan Yang, Peng Gao, Weibing Shi, Crissa Doeppke, Robert W Sykes, Jason N Burris, Joseph J Bozell, (Max) Zong-Ming Cheng, Douglas G Hayes, Nicole Labbe, Mark Davis, C Neal Stewart, Joshua S Yuan BMC Bioinformatics 2009, 10(Suppl 11):S3 (8 October 2009)

Short Report   Open Access

Measuring the combinatorial expression of solute transporters and metalloproteinases transcripts in colorectal cancer

Caroline A Kerr, Robert Dunne, Barney M Hines, Michelle Zucker, Leah Cosgrove, Andrew Ruszkiewicz, Trevor Lockett, Richard Head BMC Research Notes 2009, 2:164 (19 August 2009)

Research   Open Access Highly Accessed

Effects of lead exposure on hippocampal metabotropic glutamate receptor subtype 3 and 7 in developmental rats

Jian Xu, Huai C Yan, Bo Yang, Lu S Tong, Yu X Zou, Ying Tian Journal of Negative Results in BioMedicine 2009, 8:5 (20 April 2009)

Research article   Open Access Highly Accessed

A comprehensive collection of experimentally validated primers for Polymerase Chain Reaction quantitation of murine transcript abundance

Athanasia Spandidos, Xiaowei Wang, Huajun Wang, Stefan Dragnev, Tara Thurber, Brian Seed BMC Genomics 2008, 9:633 (24 December 2008)

Research article   Open Access Highly Accessed

Expression profile of CREB knockdown in myeloid leukemia cells

Matteo Pellegrini, Jerry C Cheng, Jon Voutila, Dejah Judelson, Julie Taylor, Stanley F Nelson, Kathleen M Sakamoto BMC Cancer 2008, 8:264 (18 September 2008)

Genes involved in DNA repair, signalling, oncogenesis and autophagy are regulated by cAMP Response Element Binding Protein (CREB) in myeloid leukemia cells, providing insights into pathogenesis and potential targets for therapy

Methodology article   Open Access Highly Accessed

Evaluation and validation of candidate endogenous control genes for real-time quantitative PCR studies of breast cancer

Roisin E McNeill, Nicola Miller, Michael J Kerin BMC Molecular Biology 2007, 8:107 (27 November 2007)

Research article   Open Access Highly Accessed

Suicide candidate genes associated with bipolar disorder and schizophrenia: An exploratory gene expression profiling analysis of post-mortem prefrontal cortex

Sanghyeon Kim, Kwang-Ho Choi, Ali Baykiz, Howard K Gershenfeld BMC Genomics 2007, 8:413 (12 November 2007)

Proceedings   Open Access Highly Accessed

Statistical tools for transgene copy number estimation based on real-time PCR

Joshua S Yuan, Jason Burris, Nathan R Stewart, Ayalew Mentewab, C Neal Stewart BMC Bioinformatics 2007, 8(Suppl 7):S6 (1 November 2007)

Methodology article   Open Access Highly Accessed

Statistical significance of quantitative PCR

Yann Karlen, Alan McNair, Sébastien Perseguers, Christian Mazza, Nicolas Mermod BMC Bioinformatics 2007, 8:131 (20 April 2007)