BMC Bioinformatics

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Open Access

Systematic assignment of thermodynamic constraints in metabolic network models

Anne Kümmel, Sven Panke and Matthias Heinemann*

BMC Bioinformatics 2006, 7:512 doi:10.1186/1471-2105-7-512

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BioMed Central: 10 citations

Methodology article   Open Access

FFCA: a feasibility-based method for flux coupling analysis of metabolic networks

Laszlo David, Sayed-Amir Marashi, Abdelhalim Larhlimi, Bettina Mieth, Alexander Bockmayr BMC Bioinformatics 2011, 12:236 (15 June 2011)

Methodology article   Open Access

Thermodynamically consistent model calibration in chemical kinetics

Garrett Jenkinson, John Goutsias BMC Systems Biology 2011, 5:64 (6 May 2011)

Research   Open Access

iBsu1103: a new genome-scale metabolic model of Bacillus subtilis based on SEED annotations

Christopher S Henry, Jenifer F Zinner, Matthew P Cohoon, Rick L Stevens Genome Biology 2009, 10:R69 (25 June 2009)

A new and validated genome-scale metabolic model of Bacillus subtilis 168, iBsu1103, is presented that has significantly improved completeness and accuracy.

Research article   Open Access

Incorporation of enzyme concentrations into FBA and identification of optimal metabolic pathways

Rajat K De, Mouli Das, Subhasis Mukhopadhyay BMC Systems Biology 2008, 2:65 (18 July 2008)

Methodology article   Open Access

Exhaustive identification of steady state cycles in large stoichiometric networks

Jeremiah Wright, Andreas Wagner BMC Systems Biology 2008, 2:61 (11 July 2008)

Methodology article   Open Access Highly Accessed

An analytic and systematic framework for estimating metabolic flux ratios from 13C tracer experiments

Ari Rantanen, Juho Rousu, Paula Jouhten, Nicola Zamboni, Hannu Maaheimo, Esko Ukkonen BMC Bioinformatics 2008, 9:266 (6 June 2008)

Metabolic flux ratios can be quickly derived using a new framework that automatically analyses 13C tracer measurements by using metabolic network models, removing the need for tedious manual analysis.

Software   Open Access Highly Accessed

anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data

Nicola Zamboni, Anne Kümmel, Matthias Heinemann BMC Bioinformatics 2008, 9:199 (16 April 2008)

Methodology article   Open Access

A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient

Francisco Llaneras, Jesús Picó BMC Bioinformatics 2007, 8:421 (30 October 2007)

Methodology article   Open Access

Optimization based automated curation of metabolic reconstructions

Vinay Satish Kumar, Madhukar S Dasika, Costas D Maranas BMC Bioinformatics 2007, 8:212 (20 June 2007)

Methodology article   Open Access

Including metabolite concentrations into flux balance analysis: thermodynamic realizability as a constraint on flux distributions in metabolic networks

Andreas Hoppe, Sabrina Hoffmann, Hermann-Georg Holzhütter BMC Systems Biology 2007, 1:23 (1 June 2007)