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Resolution: standard / high Figure 2.
Evidence from PDB structural data – SH3 domain vs. PxxPxR. 3D structure (PDB ID: 1AVZ) of a SH3 domain of FYN tyrosine kinase bound to with another protein. The sequence segments that express the "PxxPxR" motif and "GxxPxNY" motif (detected by D-STAR in this work) are highlighted in dark blue and orange respectively. The two segments correspond to actual interacting subsequences.
Tan et al. BMC Bioinformatics 2006 7:502 doi:10.1186/1471-2105-7-502 |