Figure 5.

Three different situations covered by the statistical testes in e GOn. Master-target situation: When one gene reporter list is a subset of the other list (the master list) the master-target test can be used in the comparison. Mutually exclusive target-target situation: If the gene reporters do not have any reporters in common (e.g. lists of up- vs. down regulated genes form the same experiment) the mutually exclusive target-target test can be used. Intersecting target-target situation: if the two lists compared include common gene reporters, from e.g. two experiments, then the intersecting target-target test can be used.