Table 1

The multi-functions of genes defy a straightforward estimation of the mutual information. Each gene is assigned to a vector of binary attributes A = {A1, A2, ...,

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}, described by a number ai ∈ [0,

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- 1]. The contingency table to evaluate the mutual information I(C, [A1, ...,

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]), taking all possible combinations into account, would thus include up to

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columns.

annotation

Cluster

A1

A2

A3

A4

...

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A


gene 1

1

0

1

0

0

...

1

a1

gene 2

2

0

0

0

1

...

0

a2

gene 3

1

1

0

1

0

...

0

a3

...


Steuer et al. BMC Bioinformatics 2006 7:380   doi:10.1186/1471-2105-7-380

Open Data