Table 5

Kinetic parameters for dynamic simulation

Affinity of domain

kon [M-1min-1]

koff [min-1]

Equilibrium Kd [M-1]


1 (always)

k1 = 3·105

k-1 = 6

5·104

2 (domain 1 unoccupied)

k2 = 1

k-2 = 18

5.6·10-2

2 (domain 1 occupied)

k3 = 5·107

k-3 = 24

2.1·106

3 (domain 1 unoccupied)

k4 = 1

k-4 = 12

8.3·10-2

3 (domain 1 occupied)

k5 = 1·105

k-5 = 60

1.7·103


Conzelmann et al. BMC Bioinformatics 2006 7:34   doi:10.1186/1471-2105-7-34

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