Table 5

Kinetic parameters for dynamic simulation

Affinity of domain

k_on [M^-1min^-1]

k_off [min^-1]

Equilibrium K_d [M^-1]

1 (always)

k₁ = 3·10⁵

k_-1 = 6

5·10⁴

2 (domain 1 unoccupied)

k₂ = 1

k_-2 = 18

5.6·10^-2

2 (domain 1 occupied)

k₃ = 5·10⁷

k_-3 = 24

2.1·10⁶

3 (domain 1 unoccupied)

k₄ = 1

k_-4 = 12

8.3·10^-2

3 (domain 1 occupied)

k₅ = 1·10⁵

k_-5 = 60

1.7·10³

Conzelmann et al. BMC Bioinformatics 2006 7:34   doi:10.1186/1471-2105-7-34