Figure 1.

HeatMapper screenshot. The figure shows pairwise correlations between 285 samples of patients with Acute Myeloid Leukemia, as described previously [6]. The cells in the visualization are colored by Pearson's correlation coefficient values with deeper colors indicating higher positive (red) or negative (blue) correlations. Clinical and molecular data are depicted in the columns along the original diagonal of the heatmap. Karyotype and FAB classification based on cytogenetics are depicted in the first two columns (karyotype: normal-green, inv(16)-yellow, t(8;21)-purple, t(15;17)-orange, 11q23 abnormalities-blue, 7(q) abnormalities-red, +8-pink, complex-black, other-gray; FAB M0-red, M1-green, M2-purple, M3-orange, M4-yellow, M5-blue, M6-grey). FLT3 ITD, CEBPA and NPM1 mutations are depicted in the same set of columns (red bar: positive and green bar: negative). The expression levels of CD34 (probe set: 209543_s_at) in the 285 AML patients are plotted in the last column (bars are proportional to the level of expression).