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Open AccessHighly AccessResearch article

A joint model of regulatory and metabolic networks

Chen-Hsiang Yeang1 email and Martin Vingron2 email

Center for Biomolecular Science & Engineering, University of California, Santa Cruz, 1156 High Street, Santa Cruz, CA 95064, USA

Max-Planck Institute for Molecular Genetics, 73 Ihnerstraße, Berlin, Germany

author email corresponding author email

BMC Bioinformatics 2006, 7:332doi:10.1186/1471-2105-7-332

Published: 4 July 2006

Additional files

Additional file 1:

Active paths explaining expression changes in glucose reduction, model of inferred links.

Format: EPS Size: 224KB Download file

Additional file 2:

Active paths explaining expression changes in pykF knock-out, model of inferred links.

Format: EPS Size: 224KB Download file

Additional file 3:

Active paths explaining expression changes in acetate enhancement, model of inferred links.

Format: EPS Size: 224KB Download file

Additional file 4:

Active paths explaining flux changes in pykA/pykF double knock-outs, model of inferred links.

Format: EPS Size: 224KB Download file

Additional file 5:

Active paths explaining flux changes in pgi knock-out, model of inferred links.

Format: EPS Size: 224KB Download file

Additional file 6:

Active paths explaining flux changes in zwf knock-out, model of inferred links.

Format: EPS Size: 224KB Download file

Additional file 7:

Active paths explaining expression changes in glucose reduction, model of general hypotheses.

Format: EPS Size: 214KB Download file

Additional file 8:

Active paths explaining expression changes in pykF knock-out, model of general hypotheses.

Format: EPS Size: 214KB Download file

Additional file 9:

Active paths explaining expression changes in acetate enhancement, model of general hypotheses.

Format: EPS Size: 214KB Download file

Additional file 10:

Active paths explaining flux changes in pykA/pykF double knock-outs, model of general hypotheses.

Format: EPS Size: 214KB Download file

Additional file 11:

Active paths explaining flux changes in pgi knock-out, model of general hypotheses.

Format: EPS Size: 214KB Download file

Additional file 12:

Active paths explaining flux changes in zwf knock-out, model of general hypotheses.

Format: EPS Size: 214KB Download file

Additional file 13:

The number of perturbation responses explained and contradicted by the model of inferred links with varying length, categorized by (1)types of responses (2)magnitudes of responses (3)types of paths explaining the responses.

Format: XLS Size: 20KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 14:

The number of perturbation responses explained and contradicted by the model of general hypotheses with varying length, categorized by (l)types of responses (2)magnitudes of responses (3)types of paths explaining the responses.

Format: XLS Size: 20KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 15:

The source codes of the model inference programs.

Format: ZIP Size: 147KB Download file

Additional file 16:

The data of the E. coli central carbon network and perturbation experiments.

Format: ZIP Size: 14KB Download file


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