Table 6 |
||
|
Biological Processes regulated by Ras activation. Biological Process terms significantly associated with lists of genes that were detected as differentially expressed, both before ("Pre-adj") and after ("Post-adj") adjusting for estimated changes in cell compartment sizes in the mammary glands at d4 vs. d0 following Ras activation. |
||
|
GO Term |
Pre-adj |
Post-adj |
|
|
||
|
(a) Upregulated genes |
||
|
cell surface receptor linked signal transduction |
X |
|
|
cell-matrix adhesion |
X |
|
|
DNA metabolism |
X |
|
|
inflammatory response |
X |
|
|
integrin-mediated signaling pathway |
X |
|
|
M phase of mitotic cell cycle |
X |
|
|
mRNA processing |
X |
|
|
protein amino acid phosphorylation |
X |
|
|
regulation of organismal physiological process |
X |
|
|
response to wounding |
X |
|
|
RNA processing |
X |
|
|
signal transduction |
X |
|
|
(b) Downregulated genes |
||
|
antigen presentation, endogenous antigen |
X |
|
|
ATP synthesis coupled electron transport |
X |
|
|
carbohydrate metabolism |
X |
|
|
cellular lipid metabolism |
X |
|
|
cofactor metabolism |
X |
|
|
electron transport |
X |
|
|
fatty acid metabolism |
X |
|
|
fatty acid oxidation |
X |
|
|
glycolysis |
X |
|
|
lipid metabolism |
X |
|
|
nucleoside triphosphate metabolism |
X |
|
|
organic acid metabolism |
X |
|
|
oxidative phosphorylation |
X |
|
|
proton transport |
X |
|
|
purine nucleoside triphosphate metabolism |
X |
|
|
ribonucleoside triphosphate metabolism |
X |
|
|
sterol biosynthesis |
X |
|
|
tricarboxylic acid cycle |
X |
|
|
|
||
|
Wang et al. BMC Bioinformatics 2006 7:328 doi:10.1186/1471-2105-7-328 |
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