BMC Bioinformatics

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Computational expression deconvolution in a complex mammalian organ

Min Wang, Stephen R Master and Lewis A Chodosh*

BMC Bioinformatics 2006, 7:328 doi:10.1186/1471-2105-7-328

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BioMed Central: 7 citations

Research article   Open Access Highly Accessed

Refining transcriptional programs in kidney development by integration of deep RNA-sequencing and array-based spatial profiling

Rathi D Thiagarajan, Nicole Cloonan, Brooke B Gardiner, Tim R Mercer, Gabriel Kolle, Ehsan Nourbakhsh, Shivangi Wani, Dave Tang, Keerthana Krishnan, Kylie M Georgas, Bree A Rumballe, Han S Chiu, Jason A Steen, John S Mattick, Melissa H Little, Sean M Grimmond BMC Genomics 2011, 12:441 (5 September 2011)

Research article   Open Access

Systematic Bias in Genomic Classification Due to Contaminating Non-neoplastic Tissue in Breast Tumor Samples

Fathi Elloumi, Zhiyuan Hu, Yan Li, Joel S Parker, Margaret L Gulley, Keith D Amos, Melissa A Troester BMC Medical Genomics 2011, 4:54 (30 June 2011)

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Assessing the human immune system through blood transcriptomics

Damien Chaussabel, Virginia Pascual, Jacques Banchereau BMC Biology 2010, 8:84 (1 July 2010)

This article is part of a collection on Hope of progress

Chaussabel and colleagues review the contributions of blood transcriptomics to identifying therapeutically relevant signatures of autoimmune and infectious disease, and the challenges of developing this approach into a mainstream tool.

Research article   Open Access Highly Accessed

Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression

Cecilia Williams, Luisa Helguero, Karin Edvardsson, Lars-Arne Haldosén, Jan-Åke Gustafsson Breast Cancer Research 2009, 11:R26 (8 May 2009)

Method   Open Access

Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo

Zhandong Liu, Min Wang, James V Alvarez, Megan E Bonney, Chien-chung Chen, Celina D'Cruz, Tien-chi Pan, Mahlet G Tadesse, Lewis A Chodosh Genome Biology 2008, 9:R180 (18 December 2008)

Singular value decomposition regression can detect the activation of endogenous signaling pathways, allowing the identification of pathway cross-talk.

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Gene networks driving bovine milk fat synthesis during the lactation cycle

Massimo Bionaz, Juan J Loor BMC Genomics 2008, 9:366 (31 July 2008)

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The brown adipocyte differentiation pathway in birds: An evolutionary road not taken

Nadejda V Mezentseva, Jaliya S Kumaratilake, Stuart A Newman BMC Biology 2008, 6:17 (21 April 2008)

Although birds do not have thermogenic brown adipose tissue, the developmental pathway for brown fat differentiation is still present and can be induced, indicating that brown fat evolved in a common ancestor of birds and mammals.