Figure 1.

Experimental demonstration of bounded Sig. Sig(m1) + Sig(m2) is plotted against Sig(m1 + m2), where m1 and m2 differ by one mismatch. This assumption assures the existence of a degenerate consensus motif that precisely describes {m1, m2}. A. Simulation in which k, λ ∈ [0, 50] and t = ∞. Four variations were run, in which the parameters for m1 and m2 were identical (red □), had different k (blue +), had different λ (green *) or had different k and λ (magenta x). B. Known binding sites from SCPD that differ by one mismatch. t is the number of l-length substrings in the 800 bases upstream of the translation start sites of each gene in the regulon.

Carlson et al. BMC Bioinformatics 2006 7:254   doi:10.1186/1471-2105-7-254
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