Table 2

Feed-forward and coherent loops statistics. The coherent loops were converted only if the relation between the transcription factor and a target was PromoterBinding. Table shows the number of loops with different relation types between the regulator node and the transcription factor node (Figure 1). Coherent loops are feed-forward loops with coherent regulation effects. Because many loops shared the same Expression relation between regulator and target, the number of Expression relations converted to regulation is smaller than the total number of coherent loops.

Feed-forward loops

Coherent loops

Relation from Regulator to TF

Number of unique Expression relations

Number of loops

Number of unique Expression relations

Number of loops

DirectRegulation

3242

4849

1109

1345

Expression

8911

13468

3638

4600

MolSynthesis

231

233

95

96

PromoterBinding

591

767

124

133

Regulation

10592

17246

4359

5646

Total

26689

40588

7411

12023

Yuryev et al. BMC Bioinformatics 2006 7:171   doi:10.1186/1471-2105-7-171