Methodology article
Amplification of the Gene Ontology annotation of Affymetrix probe sets
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* Corresponding author: Enrique M Muro emuro@ohri.ca
Ontario Genomics Innovation Centre, Ottawa Health Research Institute, 501 Smyth Rd, Ottawa ON, K1H 8L6, Canada
BMC Bioinformatics 2006, 7:159 doi:10.1186/1471-2105-7-159
Published: 20 March 2006Abstract
Background
The annotations of Affymetrix DNA microarray probe sets with Gene Ontology terms are carefully selected for correctness. This results in very accurate but incomplete annotations which is not always desirable for microarray experiment evaluation.
Results
Here we present a protocol to amplify the set of Gene Ontology annotations associated to Affymetrix DNA microarray probe sets using information from related databases.
Conclusion
Predicted novel annotations and the evidence producing them can be accessed at Probe2GO: http://www.ogic.ca/p2g webcite. Scripts are available on demand.