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Almost all globally essential reactions in E. coli, S. cerevisiae and S. aureus are UP or UC. The p value represents the probability that the indicated overlap would arise in a null model as discussed in the text. |
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| Organism |
E. coli |
S. cerevisiae |
S. aureus |
|
|
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| Total number of reactions |
1176 |
1579 |
865 |
| Number of globally essential reactions |
164 |
127 |
196 |
| Number of globally essential reactions that are UP or UC in the entire network |
133 (p < 10-37) |
86 (p < 10-12) |
157 (p < 10-32) |
| Number of globally essential reactions that are UP or UC in the reduced network |
156 (p < 10-62) |
117 (p < 10-41) |
182 (p < 10-58) |
Samal et al. BMC Bioinformatics 2006 7:118 doi:10.1186/1471-2105-7-118 |
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