Figure 11.

Distribution of correlations between two Pfam domains. The Pfam families are randomly selected and their correlation is calculated as described in Section Phylogenetic Analysis. The correlation represents the relatedness of two domains. Its value ranges from 0 to 1, with 1 indicating 100% similarity in the two domains' evolutionary histories and 0 no similarity. Genome protein sequences from bacteria are used in the computation. About 76% of the domain pairs have a correlation less than 0.5.