BMC Bioinformatics

official impact factor 3.03

Open Access Research article

Probabilistic annotation of protein sequences based on functional classifications

Emmanuel D Levy1,3, Christos A Ouzounis1*, Walter R Gilks2 and Benjamin Audit1,4*

Author Affiliations

1 Computational Genomics Group, The European Bioinformatics Institute, EMBL Cambridge Outstation, Cambridge CB10 1SD, UK

2 Medical Research Council Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR, UK

3 Computational Genomics Group, MRC Laboratory of Molecular Biology, Hills Rd, Cambridge CB2 2QH, UK

4 Laboratoire Joliot-Curie and Laboratoire de Physique, CNRS UMR5672, Ecole Normale Supérieure, 46 Allée d'Italie, 69364 Lyon Cedex 07, France

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BMC Bioinformatics 2005, 6:302 doi:10.1186/1471-2105-6-302

Published: 14 December 2005

Additional files

Additional File 1:

contains a more detailed description of the EC nomenclature to complement section "A database of enzymes" and the full calculation leading to equations(2) and(3) along with a figure illustrating their meaning.

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