MAS5 and GCRMA analysis. After artificially blemishing a collection of chips we excised the blemishes with Harshlight using median substitution. We compare the expression values of the blemished chips vs. the original, and the expression values after restoration with Harshlight vs. the originals. Left, GCRMA shows a substantial improvement; right, MAS5 shows a dramatic improvement.
Suárez-Fariñas et al. BMC Bioinformatics 2005 6:294 doi:10.1186/1471-2105-6-294