Schematic representation of the construction of a TMA block. TMAs are assembled by extracting cylindrical cores (using a 0.6 mm needle) from specific locations in the paraffin-embedded tissue blocks "donor" and re-embedded in an empty paraffin block "recipient" . The TMA block is then sectioned off onto slides.
Sharma-Oates et al. BMC Bioinformatics 2005 6:218 doi:10.1186/1471-2105-6-218