Table 1

Node names and descriptions for Bayes classifier.

node
description

has-function
true if the protein has the function required to fill the pathway hole, false if it does not
Shotgun-score
the number of query sequences whose BLAST output included the candidate sequence
best-E-value
negative log of the E-value for the best alignment of the candidate with a query sequence
average-rank
the average rank of the candidate sequence in the BLAST output lists (e.g., if a candidate is the best hit in each search, the average rank for the candidate is 1)
average-fraction-aligned
the average of each alignment length normalized by the length of the query sequence
pathway-directon
true if the hit is in the same directon as another gene in the same pathway; a directon is a contiguous series of genes transcribed in the same direction
adjacent-rxns
true if the hit is adjacent to one of the genes coding the enzyme for an adjacent reaction in the pathway

Green and Karp BMC Bioinformatics 2004 5:76   doi:10.1186/1471-2105-5-76