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Open Access Correction

Correction: Benchmarking tools for the alignment of functional noncoding DNA

DA Pollard1*, CM Bergman236*, J Stoye4, SE Celniker23 and MB Eisen25

Author Affiliations

1 Biophysics Graduate Group, University of California, Berkeley, CA 94720, USA

2 Department of Genome Science, Life Science Division, Lawrence Orlando Berkeley National Laboratory, Berkeley, CA 94720, USA

3 Berkeley Drosophila Genome Project, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA

4 Technische Fakultät, Universität Bielefeld, 33594 Bielefeld, Germany

5 Department of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA

6 Current address: Department of Genetics, University of Cambridge, Cambridge, CB2 3EH, UK

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BMC Bioinformatics 2004, 5:73  doi:10.1186/1471-2105-5-73

Published: 8 June 2004

First paragraph (this article has no abstract)

In follow-up studies to this work [1], we have identified an error in a single line of code responsible for parsing BLASTZ [2] alignments that affects our previously published results for this alignment tool. This error resulted in a reduction in overall alignment coverage, with a concomitant underestimation of alignment sensitivity and overestimation of alignment specificity. As BLASTZ is an important and widely used alignment tool, we present here the revised results of our performance evaluations for BLASTZ together with previously reported results for the other alignment tools studied, which have been subsequently verified (Figures 1, 2, 3, 4). The general conclusions presented in [1] remain unchanged, although the following sections concerning BLASTZ performance must be modified in light of our recent findings.