Resolution:
## Figure 10.
A) Probability densities of GFP molecules, for three versions of the
O_{R}O_{lac }promoter model. Densities were generated by accumulating statistics in runs 250000
cell cycles in duration. (Solid line) Fully discrete model. (Dashed line) Fully continuous model. (Dash-dotted line) Hybrid model: the DNA binding states are represented by discrete variables, while
all other species are continuous. All three methods produce virtually identical probability
distributions. B) Probability density for species D_{8}, for the continuous model. The hybrid and fully discrete methods produce identical
distributions in which D_{8 }spends 99.996% of the time at zero. This histogram shows that the continuous model
artificially allows negative numbers (see inset time series).
Adalsteinsson |