Figure 2.

Comparison of individual methods for interface residue prediction with the consensus method. Results are shown for Proteinase B from Streptomyces Griseus (3sgb_E), the same protein shown in Figure 1. Actual interfaces are highlighted in red. Interface residues predicted by each of five different methods are indicated as follows: P = Phylogeny (none predicted for this protein), C = Conservatism of Conservatism; S = Support Vector Machine; T = Threading; and E = Consensus. Amino acid residues present in the protein sequence, but not included in the PDB structure file, are indicated by "X"s in the sequence.