Regulatory Closeness vs. Correlation Coefficient Each point shows the mean regulatory closeness for gene pairs whose correlation in expression profile is between x and x+.01. The actual yeast data is represented by blue ● and the control data (where the mapping between genes and promoters is permuted) by red ■. The mean regulatory closeness c(X,Y) increases with the absolute value of the correlation between the expression profiles of genes X and Y.
Allocco et al. BMC Bioinformatics 2004 5:18 doi:10.1186/1471-2105-5-18