Table 1 |
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|
Comparison of GOTM with related software* |
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|
FatiGO |
Onto-Express |
GOSurfer |
GoMiner |
GOTM |
|
|
|
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|
Interface/OS |
Web |
Web |
Windows |
Windows/Mac |
Web |
|
Input Identifier |
Unigene ID, Gene symbol, Swiss-Prot ID, Ensembl ID, GenBank ID |
GenBank ID, Affymetrix probe set ID, Unigene ID |
Affymetrix probe set ID, LocusID, Unigene ID |
HUGO gene names |
LocusID, Gene symbol, Affymetrix probe set ID, UnigeneID, Swiss-Prot ID, Ensembl ID |
|
Multi-level analysis |
No |
Yes |
Yes |
Yes |
Yes |
|
Visualization of classification |
Bar chart, Table, Fixed tree |
Bar chart, Table |
Fixed tree |
Expandable tree, DAG |
Expandable tree, Bar chart, Fixed tree |
|
Statistical Analysis |
Fisher's exact test |
Binomial test, χ2 test, Fisher's exact test |
χ2 test |
Fisher's exact test |
Hypergeometric test |
|
Correction for multiple tests |
Yes |
Yes |
No |
No |
No |
|
Visualization of enriched GO categories |
Bar chart, Table |
Bar chart, Table |
Highlight in the full GOTree |
Highlight in the full DAG |
Sub-tree and DAG of enriched GO categories; Highlight in the full GOTree and bar chart |
|
Availability |
Free |
Partially free |
Free |
Free |
Free |
|
|
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* The comparison was based on the information available from individual website as of August, 2003 |
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Zhang et al. BMC Bioinformatics 2004 5:16 doi:10.1186/1471-2105-5-16 |
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