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Open AccessResearch article

Cross-species comparison significantly improves genome-wide prediction of cis-regulatory modules in Drosophila

Saurabh Sinha1 email, Mark D Schroeder2 email, Ulrich Unnerstall2 email, Ulrike Gaul2 email and Eric D Siggia1 email

1Center for Studies in Physics and Biology, The Rockefeller University, 1230 York Ave, New York, NY10021, USA

2Laboratory of Developmental Neurogenetics, The Rockefeller University, 1230 York Ave, New York, NY10021, USA

author email corresponding author email

BMC Bioinformatics 2004, 5:129doi:10.1186/1471-2105-5-129

Published: 9 September 2004

Additional files

Additional File 1:

Test Genes List of 2167 genes with expression information. (Source BDGP + literature.)

Format: TXT Size: 31KB Download file

Additional File 2:

Patterned Genes List of 286 genes with blastoderm pattern, as determined by manual inspection of in-situ expression pattern. (Source BDGP + literature.)

Format: TXT Size: 8KB Download file

Additional File 3:

Additional Genes List of 2065 genes that are ubiquitous, maternal only, or not expressed. (Source BDGP.)

Format: TXT Size: 15KB Download file

Additional File 4:

Predicted CRM's – two species List of predicted CRM's using two-species Stubb with a global, 2nd order background, sorted in decreasing order of Stubb score.

Format: HTML Size: 4.2MB Download file

Additional File 5:

Predicted CRM's – single species List of predicted CRM's using single-species Stubb with a local, 1st order background, sorted in decreasing order of Stubb score. This list of predictions, as well as that in Additional File 4 (above), is meant to be as inclusive as possible; therefore, the specificity of the lowest ranked predictions may be poor.

Format: HTML Size: 2.3MB Download file


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