Table 1 |
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Complexity of CLUSTALW. Here we show the big-O asymptotic complexity of the elements of CLUSTALW as a function of L, the typical sequence length, and N, the number of sequences, retaining the highest-order terms in N with L fixed and vice versa. |
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Step |
O(Space) |
O(Time) |
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Distance matrix |
N2 + L |
N2L2 |
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Neighbor joining |
N2 |
N4 |
|
Progressive (one iteration) |
NLP + LP = NL + L2 |
NLP + LP2 = N2 + L2 |
|
Progressive (total) |
NL + L2 |
N3 + NL2 |
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TOTAL |
N2 + L2 |
N4 + L2 |
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|
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Edgar BMC Bioinformatics 2004 5:113 doi:10.1186/1471-2105-5-113 |
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