BMC Bioinformatics

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Open Access

Improving the scaling normalization for high-density oligonucleotide GeneChip expression microarrays

Chao Lu

BMC Bioinformatics 2004, 5:103 doi:10.1186/1471-2105-5-103

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Methodology article   Open Access

Global rank-invariant set normalization (GRSN) to reduce systematic distortions in microarray data

Carl R Pelz, Molly Kulesz-Martin, Grover Bagby, Rosalie C Sears BMC Bioinformatics 2008, 9:520 (4 December 2008)

Methodology article   Open Access

Correlation test to assess low-level processing of high-density oligonucleotide microarray data

Alexander Ploner, Lance D Miller, Per Hall, Jonas Bergh, Yudi Pawitan BMC Bioinformatics 2005, 6:80 (31 March 2005)

A new graphical method for assessing the quality of low-level analysis of microarray expression data shows, among other things, that normalization, while necessary, should not be based on housekeeping genes.