Table 1

Iterative Group Analysis of gene expression during the yeast diauxic shift. Up-regulated groups.

0 h

9.5 h

11.5 h

13.5 h

15.5 h

18.5 h

20.5 h


6144 – purine base metabolism

6099 – tricarboxylic acid cycle

6099 – tricarboxylic acid cycle

3773 – heat shock protein activity

6099 – tricarboxylic acid cycle

9277 – cell wall (sensu Fungi)

3773 – heat shock protein activity

5749 – respiratory chain complex II (sensu Eukarya)

6099 – tricarboxylic acid cycle

3773 – heat shock protein activity

297 – spermine transporter activity

6950 – response to stress

6121 – oxidative phosphorylation, succinate to ubiquinone

5977 – glycogen metabolism

5749 – respiratory chain complex II (sensu Eukarya)

15846 – polyamine transport

297 – spermine transporter activity

8177 – succinate dehydrogenase (ubiquinone) activity

6950 – response to stress

6121 – oxidative phosphorylation, succinate to ubiquinone

4373 – glycogen (starch) synthase activity

3773 – heat shock protein activity

4373 – glycogen (starch) synthase activity

8177 – succinate dehydrogenase (ubiquinone) activity

15846 – polyamine transport

4373 – glycogen (starch) synthase activity

4129 – cytochrome c oxidase activity

6537 – glutamate biosynthesis

5353 – fructose transporter activity

7039 – vacuolar protein catabolism

5751 – respiratory chain complex IV (sensu Eukarya)

6097 – glyoxylate cycle

15578 – mannose transporter activity

6950 – response to stress

5749 – respiratory chain complex II (sensu Eukarya)

5750 – respiratory chain complex III (sensu Eukarya)

7039 – vacuolar protein catabolism

4129 – cytochrome c oxidase activity

6121 – oxidative phosphorylation, succinate to ubiquinone

9060 – aerobic respiration

8645 – hexose transport

5751 – respiratory chain complex IV (sensu Eukarya)

8177 – succinate dehydrogenase (ubiquinone) activity

4129 – cytochrome c oxidase activity

4396 – hexokinase activity

4396 – hexokinase activity

30162 – regulation of proteolysis and peptidolysis

5751 – respiratory chain complex IV (sensu Eukarya)

5215 – transporter activity

297 – spermine transporter activity

4364 – glutathione transferase activity

16491 – oxidoreductase activity

5977 – glycogen metabolism

6101 – citrate metabolism


For this analysis, genes were assigned to groups based on GeneOntology annotations http://www.geneontology.org webcite obtained from Affymetrix http://www.affymetrix.com/analysis/download_center.affx webcite. All groups that are changed with a minimal p-value smaller than 1/ [number of annotated genes] (1/4087 = 2.4E-4) are shown, sorted by significance. Numbers and names are the standardized GeneOntology identifiers. Groups shown in bold were also reported as changed in the original publication (DeRisi et al., 1997) Up-regulated groups

Breitling et al. BMC Bioinformatics 2004 5:100   doi:10.1186/1471-2105-5-100

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