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Iterative Group Analysis of gene expression during the yeast diauxic shift. Up-regulated groups. |
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| 0 h |
9.5 h |
11.5 h |
13.5 h |
15.5 h |
18.5 h |
20.5 h |
|
|
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| 6144 – purine base metabolism |
6099 – tricarboxylic acid cycle |
6099 – tricarboxylic acid cycle |
3773 – heat shock protein activity |
6099 – tricarboxylic acid cycle |
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| 9277 – cell wall (sensu Fungi) |
3773 – heat shock protein activity |
5749 – respiratory chain complex II (sensu Eukarya) |
6099 – tricarboxylic acid cycle |
3773 – heat shock protein activity |
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| 297 – spermine transporter activity |
6950 – response to stress |
6121 – oxidative phosphorylation, succinate to ubiquinone |
5977 – glycogen metabolism |
5749 – respiratory chain complex II (sensu Eukarya) |
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| 15846 – polyamine transport |
297 – spermine transporter activity |
8177 – succinate dehydrogenase (ubiquinone) activity |
6950 – response to stress |
6121 – oxidative phosphorylation, succinate to ubiquinone |
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| 4373 – glycogen (starch) synthase activity |
3773 – heat shock protein activity |
4373 – glycogen (starch) synthase activity |
8177 – succinate dehydrogenase (ubiquinone) activity |
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| 15846 – polyamine transport |
4373 – glycogen (starch) synthase activity |
4129 – cytochrome c oxidase activity |
6537 – glutamate biosynthesis |
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| 5353 – fructose transporter activity |
7039 – vacuolar protein catabolism |
5751 – respiratory chain complex IV (sensu Eukarya) |
6097 – glyoxylate cycle |
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| 15578 – mannose transporter activity |
6950 – response to stress |
5749 – respiratory chain complex II (sensu Eukarya) |
5750 – respiratory chain complex III (sensu Eukarya) |
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| 7039 – vacuolar protein catabolism |
4129 – cytochrome c oxidase activity |
6121 – oxidative phosphorylation, succinate to ubiquinone |
9060 – aerobic respiration |
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| 8645 – hexose transport |
5751 – respiratory chain complex IV (sensu Eukarya) |
8177 – succinate dehydrogenase (ubiquinone) activity |
4129 – cytochrome c oxidase activity |
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| 4396 – hexokinase activity |
4396 – hexokinase activity |
30162 – regulation of proteolysis and peptidolysis |
5751 – respiratory chain complex IV (sensu Eukarya) |
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| 5215 – transporter activity |
297 – spermine transporter activity |
4364 – glutathione transferase activity |
16491 – oxidoreductase activity |
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| 5977 – glycogen metabolism |
6101 – citrate metabolism |
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|
For this analysis, genes were assigned to groups based on GeneOntology annotations http://www.geneontology.org obtained from Affymetrix http://www.affymetrix.com/analysis/download_center.affx. All groups that are changed with a minimal p-value smaller than 1/ [number of annotated genes] (1/4087 = 2.4E-4) are shown, sorted by significance. Numbers and names are the standardized GeneOntology identifiers. Groups shown in bold were also reported as changed in the original publication (DeRisi et al., 1997) Up-regulated groups | ||||||
Breitling et al. BMC Bioinformatics 2004 5:100 doi:10.1186/1471-2105-5-100 |
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