Table 2

Examples for the assessment of the degree of karyotype alterations according to different categories of chromosome aberrations and calculation of a complex karyotype aberration score (CKAS).

Number of aberrations

No.

Karyotype(s)

ploidy level

numerical

balanced

unbalanced

unclassified

CKAS

1

46,XY,t(9;22)(q34;q11),t(14;20)(q11;q13.3)

0

0

2

0

0

2

2

46,XY,t(9;22)(q34;q11)/49,XY,+5,t(9;22)(q34;q11),+16,+21

0

3

1

0

0

4

3

46,XY,t(9;22)(q34;q11)/44,XY,t(9;22)(q34;q11),-8?,-11?,-11?,+mar

0

3

1

0

1

5

4

59,XXX,-1,-3,-7,-8,-9,t(9;22)(q34;q11),-11,-15,-16,-19,-20,-21, +der(22)t(9;22)(q34;q11)

1

12

1

0

0

14

5

48,XX,+5,+8,t(9;22)(q34;q11)/48,XX,+5,+8,del(9)(p13),t(9;22)(q34;q11)/ 49,XX,+5,+8,del(9)(p13),t(9;22)(q34;q11),+der(22)t(9;22)(q34;q11)

0

3

1

1

0

5

6

46,XX,t(9;22;11)(q34;q11;q13)

0

0

2

0

0

2

Bradtke et al. BMC Bioinformatics 2003 4:4   doi:10.1186/1471-2105-4-4