|
Performance of SVMHC for different HLA alleles, using MHCPEP- or SYFPEITHI-data. |
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| MHC |
Length |
Size |
Mc |
Kernel |
|
|
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| Predictions using MHCPEP |
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|
|
||||
| HLA-A1 |
9 |
28 |
0.95 |
lin |
| HLA-A*1101 |
9 |
40 |
0.74 |
poly |
| HLA-A11 |
9 |
46 |
0.75 |
rbf |
| HLA-A11 |
10 |
21 |
0.59 |
poly |
| HLA-A2 |
9 |
118 |
0.76 |
poly |
| HLA-A2 |
10 |
35 |
0.65 |
poly |
| HLA-A*2402 |
9 |
73 |
0.90 |
poly |
| HLA-A3 |
9 |
73 |
0.76 |
rbf |
| HLA-A*0201 |
9 |
184 |
0.73 |
rbf |
| HLA-A*0201 |
10 |
96 |
0.78 |
poly |
| HLA-A*3301 |
9 |
32 |
0.72 |
lin |
| HLA-A*0301 |
9 |
38 |
0.72 |
rbf |
| HLA-A*0301 |
10 |
32 |
0.77 |
lin |
| HLA-A31 |
9 |
39 |
0.79 |
poly |
| HLA-A*6801 |
9 |
42 |
0.84 |
poly |
| HLA-B7 |
9 |
32 |
0.95 |
lin |
| HLA-B8 |
9 |
26 |
0.77 |
poly |
| HLA-B*2705 |
9 |
41 |
0.93 |
lin |
| HLA-B*3501 |
9 |
67 |
0.93 |
lin |
| HLA-B*3501 |
10 |
34 |
0.96 |
poly |
| HLA-B35 |
9 |
23 |
0.71 |
lin |
| HLA-B*2703 |
9 |
22 |
0.90 |
lin |
| HLA-B*5301 |
9 |
41 |
0.95 |
lin |
| HLA-B27 |
9 |
34 |
0.91 |
rbf |
| HLA-B*2706 |
9 |
20 |
0.93 |
lin |
| HLA-B51 |
9 |
67 |
0.82 |
poly |
| HLA-B*5102 |
9 |
29 |
0.79 |
poly |
| HLA-B*0702 |
9 |
52 |
0.96 |
poly |
| HLA-B*5103 |
9 |
29 |
0.84 |
rbf |
| HLA-B*5401 |
9 |
42 |
0.98 |
lin |
| HLA-B*5101 |
9 |
35 |
0.89 |
lin |
|
|
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| Predictions using SYFPEITHI |
||||
|
|
||||
| HLA-A*0201 |
9 |
113 |
0.78 |
rbf |
| HLA-A*0201 |
10 |
40 |
0.70 |
poly |
| HLA-A1 |
9 |
28 |
0.96 |
lin |
| HLA-A3 |
9 |
73 |
0.80 |
lin |
| HLA-B*8 |
8 |
14 |
0.89 |
lin |
| HLA-B*8 |
9 |
25 |
0.79 |
lin |
| HLA-B*2705 |
9 |
29 |
1.00 |
lin |
| HLA-B7 |
9 |
23 |
0.93 |
lin |
|
The first column explains shows the HLA allele, the second the length of the binding peptides, the third the number of binders included in the training set, the fourth the performance as measured by the Matthews correlation coefficient. The final column shows what type of kernel was used in the Support Vector Machine. | ||||
Dönnes and Elofsson BMC Bioinformatics 2002 3:25 doi:10.1186/1471-2105-3-25 |
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