Table 9

Comparison of performance based on RSA range

RSA range

Predictors

Sn

Sp

Acc

MCC


Buried

iStable

0.640

0.946

0.869

0.634

I-Mutant_PDB

0.197

0.942

0.757

0.208

I-Mutant_SEQ

0.394

0.947

0.809

0.428

AUTO-MUTE_RF

0.387

0.988

0.839

0.528

AUTO-MUTE_SVM

0.254

0.989

0.806

0.403

MUPRO_SVM

0.445

0.922

0.803

0.423

PoPMuSiC2.0

0.201

0.969

0.778

0.285

CUPSAT

0.381

0.822

0.714

0.209

Partially buried

iStable

0.684

0.954

0.854

0.684

I-Mutant_PDB

0.458

0.911

0.746

0.427

I-Mutant_SEQ

0.537

0.940

0.792

0.542

AUTO-MUTE_RF

0.604

0.981

0.843

0.665

AUTO-MUTE_SVM

0.510

0.967

0.799

0.566

MUPRO_SVM

0.508

0.905

0.759

0.460

PoPMuSiC2.0

0.146

0.963

0.667

0.189

CUPSAT

0.536

0.781

0.692

0.323

Exposed

iStable

0.782

0.920

0.853

0.712

I-Mutant_PDB

0.527

0.818

0.683

0.363

I-Mutant_SEQ

0.502

0.927

0.728

0.480

AUTO-MUTE_RF

0.598

0.993

0.807

0.653

AUTO-MUTE_SVM

0.565

0.933

0.760

0.543

MUPRO_SVM

0.665

0.902

0.788

0.587

PoPMuSiC2.0

0.439

0.857

0.658

0.329

CUPSAT

0.513

0.661

0.592

0.177


Chen et al. BMC Bioinformatics 2013 14(Suppl 2):S5   doi:10.1186/1471-2105-14-S2-S5

Open Data