Table 4

Comparison of different methods for classifying exposed/buried residues on 3,553 entire TM residues of the independent test set by rASA derived from both subunit structure and complete structure (in parentheses)
Measurements TMexpo MPRAP TMX Rhythm (membrane-coil) Rhythm (channel)
MCC 0.49 (0.48) 0.33 (0.34) 0.41 (0.41) 0.30 (0.27) 0.29 (0.29)
Sensitivity 79.79% (81.29%) 62.85% (64.55%) 73.70% (73.70%) 72.43% (72.36%) 67.07% (68.18%)
Specificity 68.70% (65.69%) 70.19% (68.93%) 67.71% (67.71%) 57.64% (54.64%) 61.86% (60.42%)
Precision 75.56% (70.45%) 71.53% (67.40%) 72.18% (72.18%) 68.43% (62.57%) 68.45% (64.06%)
Accuracy 74.78% (73.51%) 66.20% (66.74%) 70.90% (70.90%) 65.91% (63.71%) 64.74% (64.37%)

Lai et al.

Lai et al. BMC Bioinformatics 2013 14:304   doi:10.1186/1471-2105-14-304

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