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Open Access Highly Accessed Research article

Lipid exposure prediction enhances the inference of rotational angles of transmembrane helices

Jhih-Siang Lai1, Cheng-Wei Cheng1, Allan Lo2*, Ting-Yi Sung1* and Wen-Lian Hsu1

Author Affiliations

1 Institute of Information Science, Academia Sinica, Taipei, Taiwan

2 Verinata Health, an Illumina Company, Redwood City, CA 94063, USA

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BMC Bioinformatics 2013, 14:304  doi:10.1186/1471-2105-14-304

Published: 11 October 2013

Additional files

Additional file 1: Dataset S1:

The rASA prediction results of the development set and the independent test set.

Format: ZIP Size: 1.5MB Download file

Open Data

Additional file 2: Table S1:

Sequence, observed angle, predicted angle, moment lengths and MAAE of the 188 TMHs in the independent test set of 21 proteins.

Format: DOCX Size: 52KB Download file

Open Data

Additional file 3: Dataset S2:

Signal peptide and topology prediction results of the independent test set from SVMSignal, TOPCONS and MemBrain.

Format: ZIP Size: 5.8MB Download file

Open Data

Additional file 4: Table S2:

Sequences, observed angles defined by residues of predicted topology (by TOPCONS), predicted angles, moment lengths and MAAE on the 155 TMHs of the independent test set.

Format: DOCX Size: 47KB Download file

Open Data

Additional file 5: Table S3:

Sequences, observed angles defined by residues of predicted topology (by MemBrain), predicted angles, moment lengths and MAAE on the 155 TMHs of the independent test set.

Format: DOCX Size: 47KB Download file

Open Data

Additional file 6: Table S4:

Evaluation measures used in this work.

Format: DOCX Size: 25KB Download file

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Additional file 7: Dataset S3:

The representative 110 multi-spanning protein chains used in this work.

Format: ZIP Size: 1004KB Download file

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Additional file 8: Text S1:

Details of LOOCV performances during model development.

Format: PDF Size: 29KB Download file

This file can be viewed with: Adobe Acrobat Reader

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